A possible new pathway for treating epileptic seizures in patients with autism

Researchers have discovered that in Nav1.2 deficient neurons, the expressions of many potassium channels are surprisingly reduced. The Nav1.2 deficiency itself doesn't cause seizures; the issue arises when the potassium channels over-compensate for the sodium channels' deficiency by shutting down too many potassium channels, making the neuron hyperexcitable, which causes seizures.

from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/09/210914184744.htm