Researchers identified a small RNA molecule called miR-766-5p that reduces expression of MYC, a critical cancer-promoting gene. This microRNA reduces levels of proteins CBP and BRD4, which are both involved in super-enhancer (SE) formation. SEs form in areas of DNA that can fuel MYC expression and tumor progression. This study provides strong evidence for developing miR-766-5p as a novel therapeutic to treat MYC-driven cancers.
from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/10/211005124701.htm
from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/10/211005124701.htm
Super-enhancers: The villain fueling certain cancers
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October 06, 2021
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