Scientists identify new therapeutic target in ovarian cancer subtype with poor prognosis

Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists discovered that loss of ARID1A function enhances a cellular stress response pathway that promotes survival of cancer cells, which become sensitive to pharmacological inhibition of this pathway.

from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/09/210921125103.htm