PARP inhibitors, used to treat patients with cancer of the breast, ovaries, prostate and pancreas, work by inducing persistent DNA gaps in tumor cells with BRCA1 and BRCA2 mutations. The discovery offers the potential to monitor tumors for the development of resistance to PARP inhibitor therapy, and to identify drug combinations that could prevent drug resistance and improve the efficacy of cancer therapies.
from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/08/210812161905.htm
from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/08/210812161905.htm
Researchers pinpoint how PARP inhibitors combat BRCA1 and BRCA2 tumor cells
![Researchers pinpoint how PARP inhibitors combat BRCA1 and BRCA2 tumor cells]()
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August 13, 2021
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