Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1). Aire-dependent central tolerance plays a critical role in maintaining male fertility by preventing autoimmune attack against multiple reproductive targets, they report.
from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/08/210819142732.htm
from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/08/210819142732.htm
New study sheds light on how an autoimmune disorder may underlie male infertility
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August 20, 2021
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