Inflammation and pressure-sensing leads to 'feed-forward' loop in osteoarthritis

An unfortunate biological 'feed-forward' loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers. Excessive loading under inflammatory conditions can create a situation that can lead to progressive cartilage degeneration.

from Latest Science News -- ScienceDaily https://www.sciencedaily.com/releases/2021/03/210322175002.htm
Inflammation and pressure-sensing leads to 'feed-forward' loop in osteoarthritis Inflammation and pressure-sensing leads to 'feed-forward' loop in osteoarthritis Reviewed by cmakigo on March 23, 2021 Rating: 5

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